Systems and methods are provided for peak to average power ratio (PAPR) reduction in multichannel digital front-ends (DFEs). A transmitter may be configured to reduce PAPR during multichannel transmission, with the reducing comprising: generating a plurality of frequency-domain symbols, each of which corresponding to a particular one of a plurality of subcarriers; assigning the subcarriers to a plurality of channels, wherein a number of channels is less than a number of subcarriers; and generating a plurality of time-domain signals corresponding to the channels. An adjustment to reduce PAPR may be applied to at least one of the time-domain signals, with the adjustment being based on symbols boundaries. The adjustment may comprise sign inversion. Adjusted and unadjusted waveforms may be generated for two or more of the time-domain signals; and selection may be made between generated adjusted waveforms based on particular criteria. The criteria may comprise lowest peak.