A system for a vehicle includes a powertrain system including an engine, a transmission, a drive shaft, and a final drive; and a controller communicably coupled to the powertrain system. The controller is structured to: receive a shift schedule for the transmission of a vehicle, the shift schedule indicating when shift events occur based on operation of the vehicle; receive vehicle operation data during operation of the vehicle, the vehicle operation data including a current combustion recipe for the engine; determine a predicted impact of a scheduled shift event on a fuel consumption rate of the vehicle based on the current combustion recipe for the engine; determine an adjustment to the scheduled shift event based on the predicted impact; and provide a command to implement the adjustment to the scheduled shift event to the transmission of the vehicle.