A method of manufacturing an organic light-emitting display apparatus includes forming a first lift-off layer comprising fluoropolymer and a moisture absorbent over a substrate comprising a first electrode; forming a photoresist over the first lift-off layer and patterning the photoresist by removing a part of the photoresist; etching the first lift-off layer in a region from which the part of the photoresist has been removed by using a first solvent to expose the first electrode; forming an organic functional layer comprising an emission layer above the first electrode and above the first lift-off layer; removing the first lift-off layer by using a second solvent; and forming a second electrode over the organic functional layer.