A method for cancellation of amplitude modulation noise using feedforward or feedback topologies. The method is adaptable to cancel amplitude modulation noise (contamination) of an input signal, including: receiving an input signal including an amplitude modulation noise signal; demodulating the amplitude modulation noise signal to generate a baseband amplitude modulation noise signal; signal processing the baseband amplitude modulation noise signal to generate a amplitude re-modulation signal; and re-modulating the input signal based on the amplitude re-modulation signal to generate an output signal, the output signal having less amplitude modulation noise than the input signal. In a feedforward embodiment, the methodology includes: signal processing the baseband amplitude modulation noise signal based on signal inversion to generate the amplitude re-modulation signal; and feeding forward the amplitude re-modulation signal to re-modulate the amplitude re-modulation signal with the input signal. In a feedback embodiment, the methodology includes: receiving the input signal in a gain controlled amplifier, generating a gain-controlled output signal; detecting the amplitude of the amplitude noise modulation signal in the gain-controlled output signal to generate a feedback amplitude noise signal; integrating the feedback amplitude noise signal to generate a gain control signal; and adjusting the gain controlled amplifier based on the gain control signal, such that the gain-controlled output signal has less amplitude modulation noise than the input signal.