A multi-view display device and a method for driving the same are provided. The multi-view display device includes a display panel and an optical grating. The display panel includes an array of a plurality of sub-pixels, and the sub-pixels in different columns, which are adjacent to each other in a row direction, are of different colors and staggered in a column direction. The array includes a plurality of pixel units, and each of the pixel units includes at least one sub-pixel in each of three adjacent columns of the sub-pixels. In each pixel unit, a middle column includes more sub-pixels than each of two side columns, amounts of the sub-pixels in the two side columns are identical, and the middle column includes one more sub-pixel than each of the two side columns. The optical grating includes a light-transmitting region corresponding to a central region of the middle column in each pixel unit.