A process for the production of multipage information leaflets or slips, the information leaflet provided with a booklet structure including two or more pages, the process including in sequence the steps of: loading and feeding of a ream of sheets printed on one or both sides, taking of a single sheet from the ream and gluing along an edge portion of the single sheet, multiple folding of the single sheet on itself along the glued portion to define a folded sheet, cutting of the folded sheet to define the multipage information leaflet with the pages connected one to the other only at a joining area in proximity of an edge, pressing of the information leaflet at the joining area, accumulation and collection of the finished information leaflets and optional rejecting of the leaflets which do not comply with the production specifications.