Invention Grant
- Patent Title: Reprogramming fibroblasts into cardiomyocytes
-
Application No.: US15030911Application Date: 2014-10-23
-
Publication No.: US10144915B2Publication Date: 2018-12-04
- Inventor: Haixia Wang , Sheng Ding
- Applicant: The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone
- Applicant Address: US CA San Francisco
- Assignee: THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE
- Current Assignee: THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE
- Current Assignee Address: US CA San Francisco
- Agency: Cooley LLP
- International Application: PCT/US2014/061970 WO 20141023
- International Announcement: WO2015/061568 WO 20150430
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N5/077 ; A61K35/34
Abstract:
Compositions and methods are described herein for chemically inducing cells that express a single pluripotency transcription factor to change their differentiation state and become cardiac cells, cardiac progenitor cells, cardiomyocytes, or a combination thereof.
Public/Granted literature
- US20160251624A1 REPROGRAMMING CARDIOMYOCYTES WITH ONE TRANSCRIPTION FACTOR Public/Granted day:2016-09-01
Information query
