A Data Center Bridged (DCB) Information Handling System (IHS) network include a plurality of switch IHSs that are connected together to provide the IHS network, and a management IHS coupled to each of the plurality of switch IHSs through a management network. The management IHS is configured to identify a plurality of data traffic flows and, for each identified data traffic flow, to determine a flow path through the IHS network. The flow paths include at least some of the plurality of switch IHSs, and the management IHS provides configuration information to each of the switch IHSs included in a flow path such that a quality of service (QoS) is provided for the data traffic flow along that flow path through the DCB IHS network according to the configuration information. Thus, the systems and methods utilize flow based networking to configure and manage DCB IHS networks.