Invention Grant
- Patent Title: Sphingosine kinase type 1 inhibitors and uses thereof
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Application No.: US15954131Application Date: 2018-04-16
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Publication No.: US10166204B2Publication Date: 2019-01-01
- Inventor: Sarah Spiegel , Robert Elliot Zipkin , Jeffrey Kroll Adams
- Applicant: Enzo Therapeutics, Inc. , Virginia Commonwealth University
- Applicant Address: US NY Farmingdale
- Assignee: Enzo Therapeutics, Inc.
- Current Assignee: Enzo Therapeutics, Inc.
- Current Assignee Address: US NY Farmingdale
- Agent Paul Diamond, Esq.
- Main IPC: A61K31/135
- IPC: A61K31/135 ; A61P1/04 ; A61K31/40 ; C07C215/28 ; C07C323/32 ; C07D263/06 ; C07D295/092 ; C07C217/64 ; C07C233/18
Abstract:
Provided are inhibitors of sphingosine kinase Type I that are useful in a number of applications, indications and diseases, as well as for monitoring pharmacokinetics and patient management. These compounds are applicable to treating tumors of the central nervous system, such as glioblastoma multiforme (GBM).
Public/Granted literature
- US20180235907A1 SPHINGOSINE KINASE TYPE 1 INHIBITORS AND USES THEREOF Public/Granted day:2018-08-23
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