Invention Grant
- Patent Title: Pharmaceutical formulations comprising substituted pyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazines for treating lysosomal storage disorders
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Application No.: US15464214Application Date: 2017-03-20
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Publication No.: US10166236B2Publication Date: 2019-01-01
- Inventor: Ethan Oren Perlstein , Nina Di Primio , Tom Aaron Hartl , Sangeetha Venkatraman Iyer , Alexander James Ludin , Tamy May Sharly Portillo Rodriguez , John Alan Tucker
- Applicant: Perlara PBC
- Applicant Address: US CA South San Francisco
- Assignee: Perlara PBC
- Current Assignee: Perlara PBC
- Current Assignee Address: US CA South San Francisco
- Agency: Sheppard Mullin Richter & Hampton LLP
- Main IPC: A61K31/4353
- IPC: A61K31/4353 ; A61K31/53 ; A61K31/724 ; A61K31/519 ; A61K31/5377
![Pharmaceutical formulations comprising substituted pyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazines for treating lysosomal storage disorders](/abs-image/US/2019/01/01/US10166236B2/abs.jpg.150x150.jpg)
Abstract:
This disclosure provides compounds, such as compounds of Formula I: pharmaceutical formulations thereof, and related methods of use for the treatment of defects of cholesterol homeostasis including lysosomal storage disorders such as Niemann-Pick Type C disease.
Public/Granted literature
- US20170281635A1 FUSED HETEROCYCLIC ORGANIC COMPOUNDS AND USES THEREOF Public/Granted day:2017-10-05
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