Invention Grant
- Patent Title: Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives
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Application No.: US15211087Application Date: 2016-07-15
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Publication No.: US10166245B2Publication Date: 2019-01-01
- Inventor: Mauro Ajani , Luigi Moro
- Applicant: Cassiopea S.P.A.
- Applicant Address: IT Lainate (MI)
- Assignee: Cassiopea S.P.A.
- Current Assignee: Cassiopea S.P.A.
- Current Assignee Address: IT Lainate (MI)
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Priority: ITMI2007A001616 20070803
- Main IPC: A61K31/573
- IPC: A61K31/573 ; C07J5/00 ; C12P33/00 ; C07J7/00 ; A61K9/00 ; A61K47/10 ; A61K47/14 ; A61K9/06 ; A61K47/06 ; A61K47/26 ; A61K47/44
Abstract:
The present invention refers to a new enzymatic process for obtaining 17α-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17α,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone-17α-propionate and 9,11-dehydro-cortexolone 17α-butanoate.
Public/Granted literature
- US20160326210A1 Enzymatic Process for Obtaining 17 Alpha-Monoesters of Cortexolone and/or its 9,11-Dehydroderivatives Public/Granted day:2016-11-10
Information query
