- Patent Title: Methods for treating lysosomal acid lipase deficiency in patients
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Application No.: US14851387Application Date: 2015-09-11
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Publication No.: US10166274B2Publication Date: 2019-01-01
- Inventor: Anthony Quinn
- Applicant: Synageva BioPharma Corp.
- Applicant Address: US MA Boston
- Assignee: ALEXION PHARMACEUTICALS, INC.
- Current Assignee: ALEXION PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Boston
- Agency: McDermott Will & Emery LLP
- Main IPC: C12N9/18
- IPC: C12N9/18 ; A61K45/00 ; C12N9/20 ; A61K38/46 ; A61K31/135 ; A61K31/366 ; A61K31/397 ; A61K31/138 ; A61K45/06
Abstract:
The present invention provides methods of treating LAL deficiency comprising administering to a mammal a therapeutically effective amount of lysosomal acid lipase with an effective dosage frequency. Methods of improving growth and liver function, increasing LAL tissue concentration, and increasing LAL activity in a human patient suffering from LAL deficiency are also provided.
Public/Granted literature
- US20160051638A1 METHODS FOR TREATING LYSOSOMAL ACID LIPASE DEFICIENCY IN PATIENTS Public/Granted day:2016-02-25
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