Invention Grant
- Patent Title: Compounds and compositions as RAF kinase inhibitors
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Application No.: US15510609Application Date: 2015-09-11
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Publication No.: US10167279B2Publication Date: 2019-01-01
- Inventor: Robert John Aversa , Matthew T. Burger , Michael Patrick Dillon , Thomas A. Dineen, Jr. , Yan Lou , Gisele A. Nishiguchi , Savithri Ramurthy , Alice C. Rico , Vivek Rauniyar , Martin Sendzik , Sharadha Subramanian , Lina Quattrocchio Setti , Benjamin R. Taft , Huw Rowland Tanner , Lifeng Wan
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Scott W. Reid
- International Application: PCT/IB2015/056989 WO 20150911
- International Announcement: WO2016/038582 WO 20160317
- Main IPC: C07D405/14
- IPC: C07D405/14 ; C07D405/12 ; C07D305/06 ; A61P35/00 ; C07D413/14

Abstract:
The present invention provides compounds of Formula (I) and (II) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.
Public/Granted literature
- US20180170917A1 COMPOUNDS AND COMPOSITIONS AS RAF KINASE INHIBITORS Public/Granted day:2018-06-21
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