Invention Grant
- Patent Title: Spirocyclic compounds as agonists of the muscarinic M1 receptor and/or M4 receptor
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Application No.: US15559375Application Date: 2016-03-21
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Publication No.: US10167284B2Publication Date: 2019-01-01
- Inventor: Miles Stuart Congreve , Giles Albert Brown , Benjamin Gerald Tehan , Mark Pickworth , Julie Elaine Cansfield
- Applicant: HEPTARES THERAPEUTICS LIMITED
- Applicant Address: GB Welwyn Garden
- Assignee: Heptares Therapeutics Limited
- Current Assignee: Heptares Therapeutics Limited
- Current Assignee Address: GB Welwyn Garden
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- Priority: GB1504675.8 20150319
- International Application: PCT/GB2016/050771 WO 20160321
- International Announcement: WO2016/147011 WO 20160922
- Main IPC: C07D471/10
- IPC: C07D471/10 ; C07D498/10 ; C07B59/00
Abstract:
This invention relates to compounds that are agonists of the muscarinic M1 and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where p, q, r, s, X, Z, Y, R1, R2, R3 and R4 are as defined herein.
Public/Granted literature
- US20180072727A1 SPIROCYCLIC COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 RECEPTOR AND/OR M4 RECEPTOR Public/Granted day:2018-03-15
Information query
