Invention Grant
- Patent Title: Boronic acid esters and pharmaceutical formulations thereof
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Application No.: US15116312Application Date: 2015-02-03
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Publication No.: US10167311B2Publication Date: 2019-01-01
- Inventor: Michael Caligiuri , Robert Lee , Guido Marcucci
- Applicant: OHIO STATE INNOVATION FOUNDATION
- Applicant Address: US OH Columbus
- Assignee: Ohio State Innovation Foundation
- Current Assignee: Ohio State Innovation Foundation
- Current Assignee Address: US OH Columbus
- Agency: Meunier Carlin & Curfman LLC
- International Application: PCT/US2015/014263 WO 20150203
- International Announcement: WO2015/117136 WO 20150806
- Main IPC: C07K5/06
- IPC: C07K5/06 ; A61K38/05 ; A61K9/127 ; C07F5/04 ; A61K47/54
Abstract:
Provided herein are boronic acid esters of boronic acid therapeutic agents, such as bortezomib. The boronic acid esters can be used to prepare liposomal formulations of boronic acid therapeutic agents with improved properties, such as enhanced stability. This disclosure, in one aspect, relates to compositions and methods of making and using the compositions.
Public/Granted literature
- US20160347791A1 BORONIC ACID ESTERS AND PHARMACEUTICAL FORMULATIONS THEREOF Public/Granted day:2016-12-01
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