Invention Grant
- Patent Title: Engineered albumin binding polypeptide
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Application No.: US15104070Application Date: 2014-12-19
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Publication No.: US10167322B2Publication Date: 2019-01-01
- Inventor: Caroline Ekblad , Fredrik Frejd , Joel Lindgren , Amelie Eriksson Karlström
- Applicant: AFFIBODY AB
- Applicant Address: SE Solna
- Assignee: AFFIBODY AB
- Current Assignee: AFFIBODY AB
- Current Assignee Address: SE Solna
- Agency: Cantor Colburn LLP
- Priority: EP13198808 20131220
- International Application: PCT/EP2014/078756 WO 20141219
- International Announcement: WO2015/091957 WO 20150625
- Main IPC: C07K14/315
- IPC: C07K14/315 ; C07K14/76 ; A61K38/00
Abstract:
The present disclosure relates to a class of engineered polypeptides having a binding affinity for albumin. In particular, the present invention relates to albumin binding polypeptides which have a high resistance to proteolytic cleavage and therapeutic use thereof. The disclosure provides an albumin binding polypeptide comprising an albumin binding motif, which motif consists of the amino acid sequence (SEQ ID NO. 1782) GXASDX5YKX8X9I X11X12AX14TVEGVX20 ALX23X24X25ILX28X29XB.
Public/Granted literature
- US20160311863A1 ENGINEERED ALBUMIN BINDING POLYPEPTIDE Public/Granted day:2016-10-27
Information query
