Nucleic acid molecules encoding insecticidal proteins
Abstract:
Improved compositions and methods for controlling pests are disclosed. In particular, nucleic acid molecules encoding novel engineered Cry1Ba (eCry1Ba) proteins having improved toxicity to lepidopteran insect pests are provided. By substituting at least one amino acid in domain I of a Cry1Ba protein an engineered Cry1Ba protein having substantially altered insecticidal properties is designed. Further, methods of making and using the ecry1Ba nucleic acid sequences, for example in transgenic plants to express eCry1B proteins to confer protection from insect damage are disclosed.
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