Invention Grant
- Patent Title: Stabilized insulin-like growth factor polypeptides
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Application No.: US14651686Application Date: 2013-12-16
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Publication No.: US10167329B2Publication Date: 2019-01-01
- Inventor: Mara Fornaro , Thomas Huber , Mauro Zurini
- Applicant: Mara Fornaro , Thomas Huber , Mauro Zurini
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Hong-Van M. Le
- International Application: PCT/IB2013/060985 WO 20131216
- International Announcement: WO2014/097116 WO 20140626
- Main IPC: C07K14/65
- IPC: C07K14/65
Abstract:
This invention is in the field of IGF-1 modifications. In particular, it relates to modified IGF-polypeptides and modified IGF-1 precursor polypeptides wherein the cleavage of E-peptide is prevented. The invention also relates to the use of such polypeptides for treating muscle diseases and disorders.
Public/Granted literature
- US20150329614A1 STABILIZED INSULIN-LIKE GROWTH FACTOR POLYPEPTIDES Public/Granted day:2015-11-19
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