Invention Grant
- Patent Title: Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
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Application No.: US12294883Application Date: 2007-04-03
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Publication No.: US10167332B2Publication Date: 2019-01-01
- Inventor: Jeffrey V. Ravetch , Yoshikatsu Kaneko , Nimmerjahn Falk
- Applicant: Jeffrey V. Ravetch , Yoshikatsu Kaneko , Nimmerjahn Falk
- Applicant Address: US NY New York
- Assignee: The Rockefeller University
- Current Assignee: The Rockefeller University
- Current Assignee Address: US NY New York
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2007/008396 WO 20070403
- International Announcement: WO2007/117505 WO 20071018
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/00 ; C07K16/06 ; C07K16/18 ; C12P21/00 ; G01N33/68 ; A61K47/68 ; A61K39/00
Abstract:
The invention provides a polypeptide containing at least one IgG Fc region region, said polypeptide having a higher anti-inflammatory activity and a lower cytotoxic activity as compared to an unpurified antibody and methods of production of such polypeptide.
Public/Granted literature
- US20100278808A1 POLYPEPTIDES WITH ENHANCED ANTI-INFLAMMATORY AND DECREASED CYTOTOXIC PROPERTIES AND RELATING METHODS Public/Granted day:2010-11-04
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