Invention Grant
- Patent Title: Production of viral vectors
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Application No.: US15236205Application Date: 2016-08-12
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Publication No.: US10167485B2Publication Date: 2019-01-01
- Inventor: Jeffrey S. Chamberlain , Dennis J. Hartigan-O'Connor
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Sheridan Ross P.C.
- Main IPC: C12N15/861
- IPC: C12N15/861 ; C12N5/10 ; C12N7/01 ; C12N15/11 ; C12N15/34 ; A61K39/235 ; C12N15/86
Abstract:
The present invention relates to methods and compositions for the production of viral vectors. In particular, the present invention provides methods and compositions for faster, higher titer and higher purity production of viral vectors (e.g. adenoviral vectors). In some embodiments, the present invention provides gutted and helper viruses with identical or similar termini. In other embodiments, the present invention provides terminal protein linked adenoviral DNA. In certain embodiments, the present invention provides template extended adenoviral DNA.
Public/Granted literature
- US20170204431A1 PRODUCTION OF VIRAL VECTORS Public/Granted day:2017-07-20
Information query
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