Enabling breakpoints on entire data structures include methods, systems, and computer program products for setting breakpoints on a plurality of memory addresses covered by a data structure. One embodiment includes receiving a reference to a data structure for which breakpoints are requested and then, based on this reference, identifying a data structure layout of the data structure. Based on the data structure layout of the data structure, a plurality of memory addresses that are covered by the data structure are identified, and the plurality of memory addresses are added to a list of breakpoints.