Invention Grant
- Patent Title: XTEN conjugate compositions and methods of making same
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Application No.: US14381199Application Date: 2013-02-27
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Publication No.: US10172953B2Publication Date: 2019-01-08
- Inventor: Volker Schellenberger , Vladimir Podust , Chia-Wei Wang , Bryant McLaughlin , Bee-Cheng Sim , Sheng Ding , Chen Gu
- Applicant: Amunix Operating Inc.
- Applicant Address: US CA Mountain View
- Assignee: Amunix Operating Inc.
- Current Assignee: Amunix Operating Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Wilson Sonsini Goodrich & Rosati
- International Application: PCT/US2013/028116 WO 20130227
- International Announcement: WO2013/130683 WO 20130906
- Main IPC: A61K47/00
- IPC: A61K47/00 ; A61K47/48 ; C07K5/02 ; A61K49/00 ; A61K38/24 ; A61K47/64
Abstract:
The present invention relates to extended recombinant polypeptide (XTEN) compositions, conjugate compositions comprising XTEN and XTEN linked to cross-linkers useful for conjugation to pharmacologically active payloads, methods of making highly purified XTEN, methods of making XTEN-linker and XTEN-payload conjugates, and methods of using the XTEN-cross-linker and XTEN-payload compositions.
Public/Granted literature
- US20150037359A1 XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME Public/Granted day:2015-02-05
Information query
