Invention Grant
- Patent Title: Bicyclic-fused heteroaryl or aryl compounds as IRAK4 modulators
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Application No.: US15754650Application Date: 2016-08-16
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Publication No.: US10174000B2Publication Date: 2019-01-08
- Inventor: Katherine Lin Lee , Christophe Philippe Allais , Christoph Martin Dehnhardt , Lori Krim Gavrin , Seungil Han , David Hepworth , Arthur Lee , Frank Eldridge Lovering , John Paul Mathias , Dafydd Rhys Owen , Nikolaos Papaioannou , Eddine Saiah , Joseph Walter Strohbach , John David Trzupek , Stephen Wayne Wright , Christoph Wolfgang Zapf
- Applicant: PFIZER INC.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent James T. Wasicak
- International Application: PCT/IB2016/054906 WO 20160816
- International Announcement: WO2017/033093 WO 20170302
- Main IPC: C07D207/273
- IPC: C07D207/273 ; C07D401/12 ; C07D401/14 ; C07D413/04 ; C07D413/14 ; C07D471/04 ; C07D491/18 ; A61K31/4015 ; A61K31/4375 ; A61K31/4709 ; A61K31/4725 ; A61K31/4745 ; A61K45/06

Abstract:
Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
Public/Granted literature
- US20180244646A1 BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS AS IRAK4 MODULATORS Public/Granted day:2018-08-30
Information query
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