Invention Grant
- Patent Title: Benzimidazole derivatives as kinase inhibitors
-
Application No.: US15179601Application Date: 2016-06-10
-
Publication No.: US10174013B2Publication Date: 2019-01-08
- Inventor: Wojciech Czardybon , Krzysztof Brzózka , Michal Galezowski , Renata Windak , Mariusz Milik , Magdalena Zawadzka , Pawel Guzik , Ewelina Wincza , Marta Prokop , Katarzyna Wiklik , Aleksandra Sabiniarz , Wieslaw Marek Cholody , Raymond Horvath , Tomasz Rzymski
- Applicant: SELVITA S.A.
- Applicant Address: PL Kraków
- Assignee: SELVITA S.A.
- Current Assignee: SELVITA S.A.
- Current Assignee Address: PL Kraków
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Priority: GB1223265.8 20121221
- Main IPC: C07D235/24
- IPC: C07D235/24 ; C07D235/30 ; C07D235/06 ; C07D235/14 ; C07D401/14 ; C07D401/12 ; C07D403/04 ; C07D403/12 ; C07D413/04 ; C07D413/12 ; C07D487/08 ; C07D401/04 ; C07D403/14 ; C07D405/12
Abstract:
The present invention relates to derivatives of benzimidazoles of formula (I) as disclosed herein as well as pharmaceutical compositions comprising said derivatives. The derivates according to the present invention are serine/threonine and tyrosine kinase-inhibitors, particularly of PIM1-3- and DYRK1A-kinases and may particularly be used in the treatment of diseases linked to these kinases, such as e.g. leukemias, lymphomas, solid tumors and autoimmune disorders.
Public/Granted literature
- US20170152249A1 NOVEL BENZIMIDAZOLE DERIVATIVES AS KINASE INHIBITORS Public/Granted day:2017-06-01
Information query
