Invention Grant
- Patent Title: Type of cytidine derivative and application thereof
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Application No.: US15527313Application Date: 2015-06-09
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Publication No.: US10174067B2Publication Date: 2019-01-08
- Inventor: Daria Yang , Haidong Wang , Xin Liu , Huijuan Wang
- Applicant: CHANGZHOU FANGYUAN PHARMACEUTICAL CO., LTD , INNER MONGOLIA PUYIN PHARMACEUTICAL CO., LTD.
- Applicant Address: CN Changzhou CN Chifeng
- Assignee: CHANGZHOU FANGYUAN PHARMACEUTICAL CO., LTD,INNER MONGOLIA PUYIN PHARMACEUTICAL CO., LTD
- Current Assignee: CHANGZHOU FANGYUAN PHARMACEUTICAL CO., LTD,INNER MONGOLIA PUYIN PHARMACEUTICAL CO., LTD
- Current Assignee Address: CN Changzhou CN Chifeng
- Agency: Anova Law Group, PLLC
- Priority: CN201410653980 20141117; CN201510167477 20150409
- International Application: PCT/CN2015/081047 WO 20150609
- International Announcement: WO2016/078397 WO 20160526
- Main IPC: C07H19/06
- IPC: C07H19/06 ; A61K9/00 ; A61K31/7068
Abstract:
The present disclosure provides a new cytidine derivative having the general formula (I), and applications thereof: As demonstrated by experiments on the growth inhibition effect of the new cytidine derivative of the present invention on HCT-116 colon cancer xenografts in tumor-bearing nude mice, the compound of the present invention has high anti-tumor activity, data of impacts on weight of nude mice bearing human colon cancer HCT-116 and data of mortality rate showed that the toxicity of the compound is comparatively low.
Public/Granted literature
- US20170355726A1 NEW TYPE OF CYTIDINE DERIVATIVE AND APPLICATION THEREOF Public/Granted day:2017-12-14
Information query
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