Invention Grant
- Patent Title: Preparation and uses of obeticholic acid
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Application No.: US15496398Application Date: 2017-04-25
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Publication No.: US10174073B2Publication Date: 2019-01-08
- Inventor: André Steiner , Heidi Waenerlund Poulsen , Emilie Jolibois , Melissa Rewolinski , Ralf Gross , Emma Sharp , Fiona Dubas-Fisher , Alex Eberlin
- Applicant: Intercept Pharmaceuticals, Inc.
- Applicant Address: US NY New York
- Assignee: Intercept Pharmaceuticals, Inc.
- Current Assignee: Intercept Pharmaceuticals, Inc.
- Current Assignee Address: US NY New York
- Agent Michelle Iwamoto-Fan
- Main IPC: A61K31/56
- IPC: A61K31/56 ; C07J9/00
Abstract:
The present invention relates to obeticholic acid: or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid is useful for the treatment or prevention of a FXR mediated disease or condition, cardiovascular disease or cholestatic liver disease, and for reducing HDL cholesterol, for lowering triglycerides in a mammal, or for inhibition of fibrosis. The present invention also relates to processes for the synthesis of obeticholic acid.
Public/Granted literature
- US20170226149A1 Preparation and Uses of Obeticholic Acid Public/Granted day:2017-08-10
Information query
