Invention Grant
- Patent Title: Highly galactosylated anti-TNF-α antibodies and uses thereof
-
Application No.: US14767117Application Date: 2014-02-13
-
Publication No.: US10174110B2Publication Date: 2019-01-08
- Inventor: Harry M. Meade , Li-How Chen
- Applicant: Laboratoire Français du Fractionnement et des Biotechnologies
- Applicant Address: FR Les Ulis
- Assignee: Laboratoire Français du Fractionnement et des Biotechnologies
- Current Assignee: Laboratoire Français du Fractionnement et des Biotechnologies
- Current Assignee Address: FR Les Ulis
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/IB2014/000692 WO 20140213
- International Announcement: WO2014/125374 WO 20140821
- Main IPC: C07K16/24
- IPC: C07K16/24 ; C07K16/04 ; A61K39/395 ; C07K16/28
Abstract:
In one aspect, the disclosure relates to highly galactosylated anti-TNF-alpha antibodies and compositions thereof. In one aspect, the disclosure relates to populations of anti-TNF-alpha antibodies with a high level of galactosylation, and compositions thereof. In one aspect, the disclosure relates to methods of production and use of highly galactosylated anti-TNF-alpha antibodies and populations of anti-TNF-alpha antibodies with a high level of galactosylation. In some embodiments, the anti-TNF-alpha antibody is adalimumab.
Public/Granted literature
- US20150368334A1 HIGHLY GALACTOSYLATED ANTI-TNF-ALPHA ANTIBODIES AND USES THEREOF Public/Granted day:2015-12-24
Information query
