Invention Grant
- Patent Title: Methods and systems for converting precursor cells into gastric tissues through directed differentiation
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Application No.: US15312939Application Date: 2015-05-27
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Publication No.: US10174289B2Publication Date: 2019-01-08
- Inventor: James Macormack Wells , Kyle William McCracken
- Applicant: Children's Hospital Medical Center
- Applicant Address: US OH Cincinnati
- Assignee: Children's Hospital Medical Center
- Current Assignee: Children's Hospital Medical Center
- Current Assignee Address: US OH Cincinnati
- Agency: Frost Brown Todd LLC
- International Application: PCT/US2015/032626 WO 20150527
- International Announcement: WO2015/183920 WO 20151203
- Main IPC: C12N5/071
- IPC: C12N5/071
Abstract:
Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. Also disclosed are methods for using the disclosed gastric cells, gastric tissues, and/or gastric organoids derived from precursor cells.
Public/Granted literature
- US20170240866A1 METHODS AND SYSTEMS FOR CONVERTING PRECURSOR CELLS INTO GASTRIC TISSUES THROUGH DIRECTED DIFFERENTIATION Public/Granted day:2017-08-24
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