Invention Grant
- Patent Title: Soluble HIV-1 envelope glycoprotein trimers
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Application No.: US15075329Application Date: 2016-03-21
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Publication No.: US10174292B2Publication Date: 2019-01-08
- Inventor: Viktoriya Dubrovskaya , Francisco Javier Guenaga , Richard Wyatt
- Applicant: International AIDS Vaccine Initiative , The Scripps Research Institute
- Applicant Address: US NY New York US CA La Jolla
- Assignee: International AIDS Vaccine Initiative,The Scripps Research Institute
- Current Assignee: International AIDS Vaccine Initiative,The Scripps Research Institute
- Current Assignee Address: US NY New York US CA La Jolla
- Agency: Duane Morris LLP
- Agent Thomas J. Kowalski; Deborah L. Lu
- Main IPC: A61K39/21
- IPC: A61K39/21 ; C12N7/00 ; A61K39/12 ; A61K39/39 ; C07K14/005 ; A61K39/00

Abstract:
The present application relates to novel HIV-1 envelope glycoproteins which may be utilized as an HIV-1 vaccine immunogens, antigens for crystallization and for the identification of broad neutralizing antibodies. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention.
Public/Granted literature
- US20160272948A1 SOLUBLE HIV-1 ENVELOPE GLYCOPROTEIN TRIMERS Public/Granted day:2016-09-22
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