Invention Grant
- Patent Title: RNA oligonucleotide and immune system enhancer comprising same
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Application No.: US15165992Application Date: 2016-05-26
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Publication No.: US10174327B2Publication Date: 2019-01-08
- Inventor: Byong-Seok Choi , Mi Kyung Lee , Janghyun Lee , Suk-Jo Kang , Eun Byeol Park
- Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Daejeon
- Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Daejeon
- Agency: Harness, Dickey & Pierce, P.L.C.
- Main IPC: A61K31/713
- IPC: A61K31/713 ; A61K48/00 ; C12N15/117
Abstract:
The present disclosure provides an RNA oligonucleotide having a helical bend structure and a use thereof. Specifically, double strands formed by a complementary binding of two sequences have a helical bend structure in the RNA oligonucleotide. The RNA oligonucleotide can increase the expression of interferon-β or ISG56 and thus can be used as an immune system enhancer.
Public/Granted literature
- US20170107518A1 RNA OLIGONUCLEOTIDE AND IMMUNE SYSTEM ENHANCER COMPRISING SAME Public/Granted day:2017-04-20
Information query
