Invention Grant
- Patent Title: Recombinant cell producing 2-hydroxyisobutyric acid
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Application No.: US13001204Application Date: 2009-04-28
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Publication No.: US10174349B2Publication Date: 2019-01-08
- Inventor: Liv Reinecke , Steffen Schaffer , Achim Marx , Markus Poetter , Thomas Haas
- Applicant: Liv Reinecke , Steffen Schaffer , Achim Marx , Markus Poetter , Thomas Haas
- Applicant Address: DE Darmstadt
- Assignee: EVONIK ROEHM GmbH
- Current Assignee: EVONIK ROEHM GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: DE102008002715 20080627
- International Application: PCT/EP2009/055089 WO 20090428
- International Announcement: WO2009/156214 WO 20091230
- Main IPC: C12P7/42
- IPC: C12P7/42 ; C12P7/62
Abstract:
The invention relates to a cell which has been genetically modified so as to be capable of producing more 2-hydroxyisobutyric acid or more polyhydroxyalkanoates containing 2-hydroxyisobutyric acid monomer units than its wild type, characterized in that 2-hydroxyisobutyric acid or polyhydroxyalkanoates containing 2-hydroxyisobutyric acid monomer units are produced via acetoacetyl-coenzyme A as intermediate and 3-hydroxybutyryl-coenzyme A as precursor.
Public/Granted literature
- US20110171702A1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID Public/Granted day:2011-07-14
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