Invention Grant
- Patent Title: Use of the ZMIZ1 marker in directing treatment and predicting survival in cancer
-
Application No.: US15071800Application Date: 2016-03-16
-
Publication No.: US10174384B2Publication Date: 2019-01-08
- Inventor: Dimitrios Mathios , Michael Lim , Patrick Ha , Chetan Bettegowda , Taeyoung Hwang , Chul-Kee Park
- Applicant: THE JOHNS HOPKINS UNIVERSITY
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University
- Current Assignee: The Johns Hopkins University
- Current Assignee Address: US MD Baltimore
- Agency: Johns Hopkins Technology Ventures
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886
Abstract:
The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions for treating cancer and predicting patient survival. In one embodiment, a method comprises (a) obtaining a biological sample from the patient; and (b) detecting hypermethylation of ZMIZ1 using primers that specifically bind to CpG island 139 at the alternative promoter of the ZMIZ1 gene.
Public/Granted literature
- US20160273050A1 USE OF THE ZMIZ1 MARKER IN DIRECTING TREATMENT AND PREDICTING SURVIVAL IN CANCER Public/Granted day:2016-09-22
Information query
IPC分类:
