The invention relates to a cutter holder (1) for a tunnel boring machine, comprising: a housing (2) comprising two cavities (26) formed in opposite walls (20), and two clamping sets (3), configured to be removably mounted on either side of the roller cutter (10) in the housing (2), and each comprising: a base plate (32), and a center wedge (34), movably mounted on the base plate (32), two side wedges (36), hinged between the base plate (32) and the center wedge (34) between a retracted position and a clamping position, wherein the side wedges (36) transversely swing and enter into the cavity (26) facing the housing (2).