Invention Grant
- Patent Title: Agent for searching for protein crystallization conditions and method of searching for protein crystallization conditions
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Application No.: US14000041Application Date: 2012-03-29
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Publication No.: US10175183B2Publication Date: 2019-01-08
- Inventor: Keiichi Kurosaka , Munehiro Kubota , Kengo Sakaguchi , Keita Ino , Itsumi Udagawa , Kazuki Iwabata , Yoichi Takakusagi , Yasutaka Seki
- Applicant: Keiichi Kurosaka , Munehiro Kubota , Kengo Sakaguchi , Keita Ino , Itsumi Udagawa , Kazuki Iwabata , Yoichi Takakusagi , Yasutaka Seki
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: KUNIMINE INDUSTRIES CO., LTD.,TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION
- Current Assignee: KUNIMINE INDUSTRIES CO., LTD.,TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2011-080944 20110331
- International Application: PCT/JP2012/058451 WO 20120329
- International Announcement: WO2012/133695 WO 20121004
- Main IPC: G01N23/20
- IPC: G01N23/20 ; C07K1/30 ; C30B7/00 ; C30B29/58 ; C30B29/54

Abstract:
An agent for searching for protein crystallization conditions, containing a water-swellable layered silicate having a fluorine atom and a hydroxyl group, wherein the fluorine atom is covalently bonded to the silicate by isomorphous substitution with the hydroxyl group. A method of searching for protein crystallization conditions, which comprises a step of mixing the agent for searching for protein crystallization conditions described above and a solution in which a protein is dissolved.
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