Invention Grant
- Patent Title: STING crystals and modulators
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Application No.: US14908019Application Date: 2014-07-31
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Publication No.: US10176292B2Publication Date: 2019-01-08
- Inventor: Dinshaw J. Patel , Thomas Tuschl , Roger Jones , Gunther Hartmann , Winfried Barchet , Thomas Zillinger , Weiyi Wang , Pu Gao , Liang Deng , Manuel Ascano, Jr.
- Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER , THE ROCKEFELLER UNIVERSITY , RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY , UNIVERSITY OF BONN
- Applicant Address: US NY New York US NY New York US NJ New Brunswick DE Bonn
- Assignee: Memorial Sloan-Kettering Cancer Center,The Rockefeller University,Rutgers, The State University of New Jersey,University of Bonn
- Current Assignee: Memorial Sloan-Kettering Cancer Center,The Rockefeller University,Rutgers, The State University of New Jersey,University of Bonn
- Current Assignee Address: US NY New York US NY New York US NJ New Brunswick DE Bonn
- Agency: Choate, Hall & Stewart LLP
- Agent Brenda Herschbach Jarrell; John P. Rearick
- International Application: PCT/US2014/049140 WO 20140731
- International Announcement: WO2015/017652 WO 20150205
- Main IPC: G06F19/16
- IPC: G06F19/16 ; G06F19/12 ; G01N33/68 ; C07K14/715 ; A61K31/352 ; A61K31/7084 ; A61K31/473 ; C07K14/70 ; C07K14/705
Abstract:
The present invention provides STING crystals. The present invention also provides STING modulators that interact with sites present in and/or defined by such crystals. The present invention also provides methods of making and using such crystals and modulators. Other aspects and/or features of the present invention will be apparent to those skilled in the art, reading the present specification.
Public/Granted literature
- US20160210400A1 STING CRYSTALS AND MODULATORS Public/Granted day:2016-07-21
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