Invention Grant
- Patent Title: Continuous process for preparing microspheres and microspheres prepared thereby
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Application No.: US14278035Application Date: 2014-05-15
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Publication No.: US10195149B2Publication Date: 2019-02-05
- Inventor: Yi Mi Kim , Sun Kyung Lim , Mi Ran Park , Young Joon Park , Seung Hee Baek , Hyun Woo Shin
- Applicant: CJ HEALTHCARE CORPORATION
- Applicant Address: KR Seoul
- Assignee: CJ HEALTHCARE CORPORATION
- Current Assignee: CJ HEALTHCARE CORPORATION
- Current Assignee Address: KR Seoul
- Agency: Seed IP Law Group LLP
- Priority: KR10-2013-0055356 20130515
- Main IPC: A61K9/16
- IPC: A61K9/16 ; A61K38/22 ; B01F3/08 ; B01F5/04 ; B01F15/02

Abstract:
The present invention relates to a continuous process for preparing microspheres and microspheres prepared thereby, and in particular, a process for preparing microspheres comprising steps of injecting a first emulsion and a second emulsion at the same time to form microspheres instantaneously, applying high pressure to the microspheres formed, and injecting the microspheres into an agitator, wherein the steps can be carried out continuously, and microspheres prepared thereby.When microspheres are prepared using the method of the present invention, scale variables, which have been the biggest disadvantage in existing preparation methods of microspheres, can be significantly reduced, drug encapsulation efficiency can be improved, and small and uniform particles can be obtained.
Public/Granted literature
- US20140341997A1 CONTINUOUS PROCESS FOR PREPARING MICROSPHERES AND MICROSPHERES PREPARED THEREBY Public/Granted day:2014-11-20
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