Systems and methods for a fluid reservoir for use with a fluid infusion device, which is automatically filled are provided. The fluid reservoir includes a barrel having a proximal end and a distal end. The fluid reservoir also includes a stopper received in the barrel and movable within the barrel from the distal end to the proximal end to dispense a fluid from a passageway of the barrel. The fluid reservoir includes at least one engagement feature defined along a portion of a perimeter of the barrel near the proximal end that removably couples the fluid reservoir to the fluid infusion device.