A pipette tip orienting apparatus includes a hopper adapted for receiving one or more pipette tips. A first alignment comb is inserted thorugh the hopper for orienting pipette tips inside the hopper. A second alignment comb is inserted through the hopper for orienting the pipette tips for delivery to a pipette tip rack. The first and second alignment combs are positioned perpendicular to one another through the hopper. Pipette tips are delivered to wells in a pipette tip rack by removing the alignment combs sequentially from the hopper.