Invention Grant
- Patent Title: Crystal forms of bedaquiline fumarate and preparation methods therefor
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Application No.: US15760090Application Date: 2015-10-20
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Publication No.: US10196360B2Publication Date: 2019-02-05
- Inventor: Jinyi Xu , Liang Zhang , Xiangyang Zhang , Xinzeng Wang , Jian Chai , Hongying Luo , Zhiqing Yang
- Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
- Applicant Address: CN
- Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
- Current Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
- Current Assignee Address: CN
- Agency: Lerner, David, Littenberg, Krumholz & Mentlik, LLP
- International Application: PCT/CN2015/092343 WO 20151020
- International Announcement: WO2017/066926 WO 20170427
- Main IPC: C07D215/227
- IPC: C07D215/227 ; B01D9/00 ; A61P31/06
Abstract:
Provided are crystal forms I, II, and III of bedaquiline fumarate, and preparation methods thereof. The crystal forms have high purity, excellent physicochemical properties, and good stability. The preparation methods can effectively improve the quality of products, and are applicable to preparation and mass production of medicines.
Public/Granted literature
- US20180265473A1 CRYSTAL FORMS OF BEDAQUILINE FUMARATE AND PREPARATION METHODS THEREFOR Public/Granted day:2018-09-20
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