Invention Grant
- Patent Title: Benzimidazole-2-piperazine heterocyclic compound, pharmaceutical composition containing the same, preparation method and use thereof
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Application No.: US14898658Application Date: 2014-06-13
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Publication No.: US10196381B2Publication Date: 2019-02-05
- Inventor: Xing Fan , Jihong Qin
- Applicant: Shanghai Huilun Life Science & Technology Co., Ltd.
- Applicant Address: CN Shanghai
- Assignee: SHANGHAI HUILUN LIFE SCIENCE &TECHNOLOGY CO., LTD
- Current Assignee: SHANGHAI HUILUN LIFE SCIENCE &TECHNOLOGY CO., LTD
- Current Assignee Address: CN Shanghai
- Agency: Andrus Intellectual Property Law, LLP
- Priority: CN201310240069 20130617
- International Application: PCT/CN2014/079827 WO 20140613
- International Announcement: WO2014/201972 WO 20141224
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D401/12
Abstract:
The present invention relates to a class of benzimidazole-2-piperazine heterocyclic derivatives, a preparation method and medical use thereof. Specifically, the present invention relates to a new benzimidazole-2-piperazine heterocyclic derivative of general Formula (I), a preparation method, a pharmaceutical composition containing the same, and use thereof as a therapeutic agent and especially as a poly(ADP-ribose)polymerase (PARP) inhibitor.
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