Invention Grant
- Patent Title: Tetrahydropyridopyrimidines and tetrahydropyridopyridines for the treatment and prophylaxis of hepatitis B virus infection
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Application No.: US15639966Application Date: 2017-06-30
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Publication No.: US10196391B2Publication Date: 2019-02-05
- Inventor: Zhanling Cheng , Min Wang , Song Yang
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agent Brian Buckwalter
- Priority: WOPCT/CN2014/095480 20141230; WOPCT/CN2015/093954 20151106
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/519 ; C07D471/04 ; A61K31/444
Abstract:
The invention provides novel compounds having the general formula: wherein R1, R2, R3, Q, U, W, Z, X and Y are as described herein, compositions including the compounds and methods of using the compounds. These compounds are HbsAg inhibitors and are useful as medicaments for the treatment or prophylaxis of HBV infection.
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