Invention Grant
- Patent Title: Ataxia telengiectasia and Rad3-related (ATR) protein kinase inhibitors
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Application No.: US15951302Application Date: 2018-04-12
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Publication No.: US10196405B2Publication Date: 2019-02-05
- Inventor: Henry Joseph Breslin , Oren Gilad
- Applicant: Atrin Pharmaceuticals LLC
- Applicant Address: US PA Ambler
- Assignee: Atrin Pharmaceuticals LLC
- Current Assignee: Atrin Pharmaceuticals LLC
- Current Assignee Address: US PA Ambler
- Agency: Baker & Hostetler LLP
- Main IPC: C07D519/00
- IPC: C07D519/00 ; C07D498/08 ; C07D515/08 ; C07D498/18 ; C07D515/18 ; A61K31/4985 ; A61K31/5377 ; A61K45/06

Abstract:
Macrocyclic compounds having the structure of Formula (A), or pharmaceutically acceptable salts thereof, are provided: wherein R1, R2, R3, R4 and R5 are defined herein. Also provided are pharmaceutical compositions comprising the macrocyclic compound and methods for treating cancer in a patient comprising administering to the patient the macrocyclic compound.
Public/Granted literature
- US20180230168A1 Ataxia Telengiectasia And Rad3-Related (ATR) Protein Kinase Inhibitors Public/Granted day:2018-08-16
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