Invention Grant
- Patent Title: Modulation of gene expression and screening for deregulated protein expression
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Application No.: US15288415Application Date: 2016-10-07
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Publication No.: US10196639B2Publication Date: 2019-02-05
- Inventor: Igor Vorechovsky , Jana Kralovicova
- Applicant: University of Southampton
- Applicant Address: GB Hampshire
- Assignee: University of Southampton
- Current Assignee: University of Southampton
- Current Assignee Address: GB Hampshire
- Agency: Wilson, Sonsini, Goodrich & Rosati
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; C12Q1/6883 ; C12Q1/6886 ; C12N5/00
Abstract:
Disclosed herein include compositions and methods of modulating protein expression that utilizes an activator or a repressor of a non-sense mediated RNA decay switch exon (NSE). In some embodiments, also included herein are compositions and methods of modulating protein expression that uses an agent that targets a transposed element.
Public/Granted literature
- US20170101641A1 MODULATION OF GENE EXPRESSION AND SCREENING FOR DEREGULATED PROTEIN EXPRESSION Public/Granted day:2017-04-13
Information query
