Invention Grant
- Patent Title: Oligonucleotide compositions with enhanced efficiency
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Application No.: US16015009Application Date: 2018-06-21
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Publication No.: US10196640B1Publication Date: 2019-02-05
- Inventor: Tod Woolf , Margaret Taylor
- Applicant: Life Technologies Corporation
- Applicant Address: US CA Carlsbad
- Assignee: LIFE TECHNOLOGIES CORPORATION
- Current Assignee: LIFE TECHNOLOGIES CORPORATION
- Current Assignee Address: US CA Carlsbad
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; A61K31/70 ; C12N15/113 ; A61K31/713 ; C12N15/11 ; C12N5/00
Abstract:
The oligonucleotide compositions of the present invention make use of combinations of oligonucleotides. In one aspect, the invention features an oligonucleotide composition including at least 2 different oligonucleotides targeted to a target gene. This invention also provides methods of inhibiting protein synthesis in a cell and methods of identifying oligonucleotide compositions that inhibit synthesis of a protein in a cell.
Public/Granted literature
- US20190017051A1 OLIGONUCLEOTIDE COMPOSITIONS WITH ENHANCED EFFICIENCY Public/Granted day:2019-01-17
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