Invention Grant
- Patent Title: Methods and compositions for treatment of a genetic condition
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Application No.: US15872644Application Date: 2018-01-16
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Publication No.: US10196652B2Publication Date: 2019-02-05
- Inventor: Anthony Conway , Gregory J. Cost , Russell Dekelver , Edward J. Rebar , Andreas Reik , Fyodor Urnov , Jianbin Wang , H. Steve Zhang
- Applicant: Sangamo Therapeutics, Inc.
- Applicant Address: US CA Richmond
- Assignee: Sangamo Therapeutics, Inc.
- Current Assignee: Sangamo Therapeutics, Inc.
- Current Assignee Address: US CA Richmond
- Agency: Pasternak Patent Law Susan Abrahamson
- Main IPC: C12N15/90
- IPC: C12N15/90 ; C12N15/11 ; C07K2/00 ; C12N9/22
Abstract:
Methods and compositions comprising a CRISPR/Cas nuclease that cleaves a T cell receptor (TCR) gene and/or human leukocyte (HLA) gene, the nuclease comprising a cleavage domain and a single guide RNA that binds to a target site in the TCR and/or HLA gene.
Public/Granted literature
- US20180148740A1 METHODS AND COMPOSITIONS FOR TREATMENT OF A GENETIC CONDITION Public/Granted day:2018-05-31
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