A cold end heat exchanging device and a semiconductor refrigerator having the cold end heat exchanging device. The cold end heat exchanging device comprises a cold end heat exchanging part and a plurality of refrigerant pipelines. The cold end heat exchanging part defines an inner cavity or a conduit for containing a gas-phase and liquid-phase co-existing refrigerant. Each refrigerant pipeline is provided with an evaporation section that is downwards bent and extends in a vertical plane and has a closed tail end, and a connection section that is upwards bent and extends from a starting end of the evaporation section and is connected to the inner cavity or the conduit. Evaporation sections of at least some refrigerant pipelines of the plurality of refrigerant pipelines are distributed in two vertical planes that are perpendicular to each other.