Invention Grant
- Patent Title: Serum antibody assay for determining protection from malaria, and pre-erythrocytic subunit vaccines
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Application No.: US15858560Application Date: 2017-12-29
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Publication No.: US10197577B2Publication Date: 2019-02-05
- Inventor: Philip Felgner , Stephen L. Hoffman , Robert Seder , Joseph J. Campo, Jr.
- Applicant: Sanaria Inc. , Antigen Discovery, Inc. , The United States of America, as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US MD Rockville US CA Irvine US DC Washington
- Assignee: Sanaria Inc.,Antigen Discovery, Inc.,The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: Sanaria Inc.,Antigen Discovery, Inc.,The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Rockville US CA Irvine US DC Washington
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K39/00
- IPC: A61K39/00 ; G01N33/68 ; A61K39/015 ; G01N33/569
Abstract:
Disclosed herein are diagnostic methods and compositions for identifying individuals that are protected against Plasmodium falciparum caused malaria. Such methods are particularly useful for determining not only the protective efficacy of Pf whole parasite vaccines for individual subjects, but also within populations of vaccinated subjects. Also disclosed herein are subunit vaccines comprising at least one Pf immunologic determinant for protection against Plasmodium-caused malaria.
Public/Granted literature
- US20180231566A1 SERUM ANTIBODY ASSAY FOR DETERMINING PROTECTION FROM MALARIA, AND PRE-ERYTHROCYTIC SUBUNIT VACCINES Public/Granted day:2018-08-16
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