A mesoscopic solar cell, including: a conductive substrate, a hole blocking layer, a mesoporous nanocrystalline layer, an insulation separating layer, and a hole collecting layer, and perovskite light absorption materials. The hole blocking layer, the mesoporous nanocrystalline layer, the insulation separating layer, and the hole collecting layer are sequentially laminated on the conductive substrate. The perovskite semiconductor materials are filled in the mesoporous nanocrystalline layer, the insulation separating layer, and the hole collecting layer, which enables the mesoporous nanocrystalline layer to be an active light absorption layer operating as a photoanode, and enables the insulation separating layer to be a hole transporting layer.