Invention Grant
- Patent Title: Process for reducing contaminating Michael acceptor levels in oxycodone and other compositions
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Application No.: US15225699Application Date: 2016-08-01
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Publication No.: US10201174B2Publication Date: 2019-02-12
- Inventor: Jules A. Shafer , Vladislav V. Telyatnikov , Hao Wang
- Applicant: Controlled Chemicals, Inc.
- Applicant Address: US PA Colmar
- Assignee: Controlled Chemicals, Inc.
- Current Assignee: Controlled Chemicals, Inc.
- Current Assignee Address: US PA Colmar
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A23L5/20 ; C07D489/02 ; C07D489/08 ; G01N30/74 ; G01N33/02 ; G01N33/15 ; G01N30/02
Abstract:
The present invention relates to processes for removal of Michael acceptors from certain compositions wherein the composition is treated with a thiol-containing compound under conditions sufficient to remove Michael acceptors and the resulting thiol-Michael adducts. Certain embodiments of the present invention enable quantification and/or removal of Michael acceptors and/or Michael acceptor precursors.
Public/Granted literature
- US20170027199A1 PROCESS FOR REDUCING CONTAMINATING MICHAEL ACCEPTOR LEVELS IN OXYCODONE AND OTHER COMPOSITIONS Public/Granted day:2017-02-02
Information query
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