Invention Grant
- Patent Title: Therapeutic compositions and methods for treating HIV including identification and manipulation of particular domains associated with immunogenicity
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Application No.: US15694388Application Date: 2017-09-01
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Publication No.: US10201603B2Publication Date: 2019-02-12
- Inventor: Phillip Berman , Sara O'Rourke , William Scott
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic, Field & Francis LLP
- Agent Shweta Chandra
- Main IPC: C07K14/005
- IPC: C07K14/005 ; C07K14/16 ; A61K39/21 ; C07K14/00 ; A61K38/00 ; A61K38/16 ; G01N33/569 ; A61K39/12

Abstract:
Selection of HIV vaccine antigens by use of intrapatient sequence variation to identify mutations in the HIV envelope glycoprotein that affect the binding of broadly neutralizing antibodies and polypeptides identified by these methods.
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